if you have the experience, use Access
why?
its multi user, so the same data can be viewed on more than one device at any one time.
reporting is straightforward and simple, or can be straightforward and complex, or can horrendously complex but still dooable
you are less prone to subtle data errors that can creep in if you use a spreadsheet to store data (Im not knocking spreadsheets, they do a fantastic job at analysing data, however they can be a frightmare if you use them as the original source storing data).
modern versions of Access can run licence free using Access runtime, meaning that you may not need multiple copies of Access.
data validation and integrity is almost built in to a database, its not a strong point in a spreadsheet
you can always dump data from Access into a spreadsheet if required, its tricky to go the other way.