providing you have physical access (permission) to read or write those data sources you can do what ever you like.
As far as I'm aware ASP like other such languages doesn't care what db storage method it talks to, providing in it knows how to talk to the db.
It does mean that you will be running 2 connections to your data for each instance of your script, so you may have a resource issue, especailly if you don't correctly clean up after the connection is finished with.