On AIX, we had to chage the data and stack settings of instance id, data to unlimited, stack to 32768. It may help to find out what the values should be for your platform.
You may need to make some configuration changes since the pointers become larger. We noticed that the number of deadlocks increased. There were some other config changes which we made, however, we did add memory to the servers. We increased FCM parms, sortheap, doubled buffpage, dbheap.
HTH