It depends on your site policies and the volume of data:
If the data volume is small, then you can export data to ixf/del files and do import to the zos. Note, you need DB2 Connect license to do this.
You can create "federated" link(called DDF on zos, iirc) from the zos to the luw, and then do "insert into...select from " or load from cursor.
you can create a federated link from luw to zos and issue insert into ..select * from ..
you can "export" the data from luw to fixed width files, ftp over to mainframe and run the LOAD utility.