WPS uses a set of 6 databases, which we have created on DB2 (db2 - version 9.5 fixpack 2a)

During some operation, following error is thrown, seen on UI:

om.ibm.db2.jcc.a.en: [jcc][t4][2030][11211][3.52.95] A communication error occurred during operations on the connection's underlying socket, socket input stream,
or socket output stream. Error location: Reply.fill(). Message: A remote host did not respond within the timeout period.. ERRORCODE=-4499, SQLSTATE=08001
at com.ibm.db2.jcc.a.ad.a(ad.java:319)
at com.ibm.db2.jcc.t4.a.a(a.java:365)
at com.ibm.db2.jcc.t4.a.a(a.java:360)
at com.ibm.db2.jcc.t4.ab.b(ab.java:202)
at com.ibm.db2.jcc.t4.ab.c(ab.java:244)
at com.ibm.db2.jcc.t4.ab.c(ab.java:355)
at com.ibm.db2.jcc.t4.ab.v(ab.java:1140)
at com.ibm.db2.jcc.t4.fb.b(fb.java:135)
at com.ibm.db2.jcc.t4.c.Rb(c.java:291)
at com.ibm.db2.jcc.a.p.h(p.java:306)
at com.ibm.db2.jcc.t4.a.h(a.java:506)
at com.ibm.db2.jcc.a.p.a(p.java:204)
at com.ibm.db2.jcc.a.sl.e(sl.java:3187)
at com.ibm.db2.jcc.a.sl.Ob(sl.java:569)
at com.ibm.db2.jcc.a.sl.executeQuery(sl.java:543)

WPS, fails to connect to its databases on another server (the DB server) due to timeout period.

Is there any parameter change required from DB2 side.
plz help..

I would first try to verify that you can connect to each of the 6 databases manually.

yes, I can connect to the 6 databases
the WPS is configured to connect to the databases using instance ID itself.
(this is on AIX platform)