If you are taking a backup of the database and restoring it to the same location (ie, host, port etc), I do not see a reason to reconfigure replication. The target tables and control tables (subscription, subs_set etc) if defined in the target db will be restored automatically.
If capture is involved too, some extra steps may be needed to reset the capture control tables for the new log files. [ Cant recall steps ]. Do you have capture on this db?