A BLOB is a value in a database. So the only way to get such values into the database or to retrieve them from there is through the means provided by the database system. That means: SQL.
What you could probably do is to store the data in a file in the file system and only the path in the database. Then you can access the data directly and bypass the database system. But in this case you'd probably use a VARCHAR and not a BLOB to store the path to the file.