Hi,
We have DB2 databases listed on z/OS. We want to work with aliases in DB2 LUW, but physical databases resides on z/OS. Can we create alias to those in LUW DB2? Please advise. Does it work?

Thank you.

question is not very clear
you can catalog the z-db on any station, as long as db2 connect is installed
while doing the catalog you can give this db an alias name
if db2 connect as gateway - other db2 luw clients can connect to this z-db by use of db2 connect as gateway
all details are
DB2 Connect