I wasn't sure how to code "In Excel VBA, you could multiply the cell value by 1 which will ensure that it will become a number." (I'm too much a newbie). Was going to ask you how, but, between my posting and now I found out about the .HasFormula and then .Formula properties.
Here's the solution I came up with. The code follows the DoCmd.TransferSpreadsheet code:
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'Set E Column Formula Property To The Formula
For i = 2 To iLastRow
strRow = Format(iLastRow, "0")
strRange = "E" & strRow
strTemp = "=If(D" & strRow & "<>(F" & strRow & "+H" & strRow & "+J" _
& strRow & "+L" & strRow & "),""*"","""")"
xlWSh.Range(strRange).Formula = strTemp
Next i
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Rich - BTW: Would you please expand on your suggestion? Where do I place the code? What does the code look like? I'm sure this technique will come in handy some day, no sense passing up an opportunity to learn it now.