One approach is to first import the data into a staging table.
Then, run a query that copies data from the staging table into the final table, using the case construct or the NULLIF function in the select subquery, to insert a null in the target field when the source field is an empty string. (or, more accurately, when the staging table source field contains just the two quotation characters "")
Code:
Select field1, NULLIF(field2, '""') AS field2, NULLIF(field3, ''"") as field3 FROM staging_table