I am creating a web-based database application and need yoru thoughts on the best structure for the DB tables to allow best functionality and reasonable speed. Here are the details:

Microsoft-IIS/6.0 server
Access 2003 database
About 1.5 million records arranged by geographic regions of the state
About 30,000 records for each of 50 regions
About 50 fields in main table

Should I
Set up 50 separate databases?
Set up 50 separate tables in the same DB?
Set up one main DB table?