RSA bsafe might be one consideration but they need you alter your applications and possibly the schema/db objects benefit is it can be column/row level encrypt. If you just want to achieve security compliance, storage/file encryption is perhaps a better option. At least you save time for 2nd development. brocade has a FC-SAN switch supporting encryption. if your db (sqlserver?) is not on SAN you might go and take a look at bloombase or safenet.