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Unanswered: Cloning Sybase database
How do U clone a sybase database from One Storage to another storage devices whith minimal downtime.
Total database size 150 GB on Unix
If you are doing this on a single machine then you can use "disk mirror".
If you need to clone the system to a different machine then you could use database dumps (but you will incur some downtime) or replication server (minimal downtime).
A little more information on what you want to achieve would help us in getting you appropriate information.